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Cat. No. Product Name Target Signaling Pathways
T7748 Dermorphin TFA

皮啡肽三氟乙酸盐

Others; Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience; Others
Dermorphin TFA 是在两栖类皮肤中发现的天然七肽,是 μ-阿片受体激动剂,可用于抑制神经痛。
T15781 LP-935509

Serine/threonin kinase; AAK1 (AP2 associated kinase 1) Cell Cycle/Checkpoint; Metabolism; Neuroscience
LP-935509 是一种选择性的、具有脑渗透的、小分子的衔接蛋白-2 相关激酶1 (AAK1) ATP 竞争性抑制剂,其 IC50=3.3 nM,Ki=0.9 nM。它是一种 BIKE 的有效抑制剂 (IC50=14 nM) 和中度的 GAK 抑制剂 (IC50=320 nM)。它能够逆转 SNL 手术后的疼痛。
T7404 Dermorphin

皮啡肽

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
Dermorphin 是在两栖类皮肤中发现的天然七肽,是 μ-阿片受体激动剂,可用于抑制神经痛。
T70340 JHU-58

JHU-58 is a novel dipeptide MrgC agonist. JHU-58 inhibited both mechanical and heat hypersensitivity in rats after an L5 spinal nerve ligation (SNL). JHU58 attenuated the evoked excitatory postsynaptic currents in substantia gelatinosa (SG) neurons in wild-type mice, but not in Mrg knockout mice, after peripheral nerve injury.
T83213 AC-099

AC-099 hydrochloride(化合物 3)作为NPFF2R的选择性全激动剂(EC50=1189 nM)和NPFF1R的部分激动剂(EC50=2370 nM),可降低大鼠脊神经结扎引起的痛觉超敏。
T35461 δ14-Triamcinolone acetonide

δ14-Triamcinolone acetonide is a potential impurity found in commercial preparations of triamcinolone acetonide. Triamcinolone acetonide is a synthetic corticosteroid. It decreases cytokine levels, the firing rate of sensory neurons, and mechanical hypersensitivity in a rat spinal nerve ligation model when used at a dose of 1.5 mg/kg prior to and following surgery for three days. Triamcinolone acetonide also decreases outflow facility in a mouse model of steroid-induced glaucoma when 20 μl of a ...

化合物

Dermorphin TFA
Cat.No: T7748
Synonym: 皮啡肽三氟乙酸盐
Target: Others, Opioid Receptor
LP-935509
Cat.No: T15781
Synonym:
Target: Serine/threonin kinase, AAK1 (AP2 associated kinase 1)
Dermorphin
Cat.No: T7404
Synonym: 皮啡肽
Target: Opioid Receptor
JHU-58
Cat.No: T70340
Synonym:
Target:
AC-099
Cat.No: T83213
Synonym:
Target:
δ14-Triamcinolone acetonide
Cat.No: T35461
Synonym:
Target:
TargetMol Loading
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